منابع مشابه
Insights Into Statin Intolerance
Stephen Kopecky, MD, FACC, FACP; Seth Baum, MD, FACC, FACPM, FAHA, FNLA; JoAnne M. Foody, MD, FACC, FAHA; Michael Koren, MD, FACC; James McKenney, PharmD, FNLA; Laurence Sperling, MD, FACC, FAHA, FACP; Nathan D. Wong, PhD, MPH, FACC, FAHA; Statin Intolerance Roundtable Participants Division of Cardiovascular Diseases (Kopecky), Mayo Clinic, Rochester, Minnesota; Women’s Preventive Cardiology Ce...
متن کاملMolecular mechanisms of statin intolerance
Statins reduce cardiovascular morbidity and mortality in primary and secondary prevention. Despite their efficacy, many persons are unable to tolerate statins due to adverse events such as hepatotoxicity and myalgia/myopathy. In the case of most patients, it seems that mild-to-moderate abnormalities in liver and muscle enzymes are not serious adverse effects and do not outweigh the benefits of ...
متن کاملStatin Intolerance: the Clinician’s Perspective
Muscle problems and other adverse symptoms associated with statin use are frequent reasons for non-adherence and discontinuation of statin therapy, which results in inadequate control of hyperlipidemia and increased cardiovascular risk. However, most patients who experience adverse symptoms during statin use are able to tolerate at least some degree of statin therapy. Given the profound cardiov...
متن کاملThe Impact of Statin Intolerance in Lipid Clinic Patients
Context: Cardiovascular disease is a very common and serious problem in the western world. Statin drug therapy is used in primary, secondary prevention and familial hypercholesterolemia. However, these are frequently associated with adverse effects, causing poor adherence and thus putting patients at risk for future cardiovascular events. Aim: The objective of this study was to review the stati...
متن کاملAn assessment by the Statin Intolerance Panel: 2014 update.
This article from the National Lipid Association Statin Intolerance Panel provides a framework for understanding statin intolerance and makes general recommendations for health professionals. For specific guidance on adverse events related to muscle, liver, cognition, and glucose metabolism, one should refer to the other reports of the Statin Safety Task Force for those topics. Although statin ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2017
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2017.01.019